Enhancement of Lumbar Fusion and Alleviation of Adjacent Segment Disc Degeneration by Intermittent PTH(1-34) in Ovariectomized Rats
نویسندگان
چکیده
منابع مشابه
Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat
BACKGROUND Intervertebral disc (IVD) degeneration and pathological changes in the spinal cord are major causes of back pain. In addition to its well-established anti-resorptive effect on bone, calcitonin (CT) potentially exerts protective effects on IVD degeneration in ovariectomized rats. However, possible therapeutic effects of CT on lumbar fusion-induced adjacent-segment disc degeneration (A...
متن کاملincidence of microscopic lumbar intervertebral disc calcification and its correlation to endplate degeneration type and disc histopathologic angiogensis
چکیده ندارد.
15 صفحه اولAdjacent segment degeneration following spinal fusion for degenerative disc disease.
Fusion has become the standard of care for numerous pathologic conditions of the spine over the past 50 years. Instrumented thoracolumbar fusion for adolescent and adult spinal deformity has enjoyed great success in arresting the progression of and correcting scoliotic deformity. In the cervical spine, decompression and fusion have provided a greater than 90% likelihood of relieving radicular s...
متن کاملDoes Disc Space Height of Fused Segment Affect Adjacent Disc Degeneration in Anterior Lumbar Interbody Fusion? A Radiological Study
BACKGROUND The restoration of disc space height (DSH) is essential in anterior lumbar interbody fusion (ALIF), while it is unclear whether the reduction of DSH may alter the mechanical status and adversely affect adjacent segment, and few literatures focused on the subject. METHODS Ninety five patients who had undergone ALIF for degenerative disc disease at our institution between March 2004 ...
متن کاملAdjacent segment degeneration in the lumbar spine.
BACKGROUND A primary concern after posterior lumbar spine arthrodesis is the potential for adjacent segment degeneration cephalad or caudad to the fusion segment. There is controversy regarding the subsequent degeneration of adjacent segments, and we are aware of no long-term studies that have analyzed both cephalad and caudad degeneration following posterior arthrodesis. A retrospective invest...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2015
ISSN: 0884-0431
DOI: 10.1002/jbmr.2736